San Francisco 49ers vs Detroit Lions Prediction for January

In the pivotal NFC Championship Game, the stage is set for a Sunday night spectacle as the Detroit Lions take on the San Francisco 49ers, vying for a coveted spot in the Super Bowl. The Detroit Lions, though perceived as the underdogs, are determined to defy expectations and pull off an astonishing upset against the powerful 49ers.
Written By
Carlos Reyes
Jan 28, 2024
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The previous weekend in the NFL featured two enthralling encounters. The Detroit Lions squared off against the Tampa Bay Buccaneers, triumphing with a score of 31-23. Despite being outperformed in yardage, the Lions skillfully won the battles of turnovers and time possession, swaying the outcome in their favor. Meanwhile, the San Francisco 49ers battled the Green Bay Packers, clinching a close 24-21 victory. The 49ers slightly outperformed in yardage and crucially controlled the turnover aspect. Their remarkable ability to convert 10 of their 16 third-down attempts was key in maintaining drives and maximizing scoring chances.

San Francisco 49ers vs Detroit Lions
San Francisco 49ers vs Detroit Lions

The game is scheduled for 18:30 ET on Sunday, January 28, 2024, corresponding to 11:30 p.m. GMT, at Levi’s Stadium in Santa Clara, California.

This article provides sports betting insights and predictions for the upcoming game between the Detroit Lions and San Francisco 49ers on January 28. It includes the latest betting odds, significant statistics, team updates, and probable starting lineups.

San Francisco 49ers vs Detroit Lions latest odds on betting sites 

The moneyline odds for the San Francisco 49ers are set at 1.29 (-345 in American odds), and for the Detroit Lions, the moneyline odds are at 3.90 (+290).


  • Over 52.0 points: 1.95 (-105)
  • Under 52.0 points: 1.92 (-109)


  • San Franciso 49ers -7.0: 1.95 (-115)
  • Detroit Lions +7.0: 2.00 (+100)

San Francisco 49ers vs Detroit Lions match preview and statistics

San Francisco 49ers: For the San Francisco 49ers, quarterback Brock Purdy achieved another playoff victory, although his performance wasn’t at its peak. Purdy completed 23 of 39 passes, amassing 252 yards and notably connecting with George Kittle for a touchdown. Despite this, he narrowly avoided turnovers on two occasions and missed several key throws.

Purdy led a decisive 69-yard touchdown drive, marked by a 12-play series featuring significant passes and a key 9-yard run, setting up the winning score.

Defensively, linebacker Dre Greenlaw was a standout, intercepting Jordan Love twice. His contribution included nine solo tackles, three defensive stops, and consistent pressure on the ball carrier, demonstrating his value to the team.

The 49ers, ranking first overall, showcased their resilience in a come-from-behind victory in their first playoff match, proving their ability to recover under pressure.

Team news includes the absence of tight end Ross Dwelley, wide receiver Danny Gray, and defensive lineman Clelin Ferrell. Wide receiver Deebo Samuel and defensive tackle Arik Armstead are questionable.

Detroit Lions: For the Detroit Lions, quarterback Jared Goff was notably efficient, completing 30 of 43 passes for 287 yards and two touchdowns. Wide receiver Amon-Ra St. Brown was key with eight receptions, including a critical touchdown.

Running back Jahmyr Gibbs added dynamism to the Lions’ ground game, highlighted by a 31-yard touchdown run, ending with 74 yards.

Center Frank Ragnow, despite an injury, was resilient, especially against Buccaneers’ Vita Vea in a crucial touchdown run by Reynolds.

The Lions’ defense was impactful, with safety Ifeatu Melifonwu and rookie Brian Branch combining for significant sacks, putting pressure on the Buccaneers’ quarterback.

Team news includes the absences of tight end James Mitchell, cornerback Jerry Jacobs, and guard Jonah Jackson. Wide receiver Kalif Raymond and center Frank Ragnow are questionable.

Lions vs 49ers H2H

Throughout both regular season and postseason play, the 49ers and Lions have competed against each other in 68 games. In these matchups, the 49ers hold an overall record of 39 wins, 28 losses, and 1 tie against the Lions. Presently, the 49ers lead the series against the Lions by a margin of two games.

San Francisco 49ers vs Detroit Lions key players

Brock Purdy: The Niners’ journey to the NFC Championship, despite not starting a top overall draft pick at quarterback, can be largely attributed to their 262nd pick from the 2022 draft’s seventh round, who has emerged as an NFL sensation. Over 16 games this season, Brock Purdy has impressively recorded a passer rating of 113.0, thrown for 4,280 yards, and achieved 31 touchdowns against 11 interceptions.

Jared Goff: The Lions’ reach to the NFC Championship Game and their potential first-ever Super Bowl appearance can be credited to quarterback Jared Goff’s outstanding performance throughout the regular season and playoffs. In 17 games this season, Goff has completed passes totaling 4,575 yards, thrown 30 touchdowns, and 12 interceptions, culminating in a quarterback rating of 97.9.

Detroit Lions vs San Francisco 49ers predictions

The Lions’ offensive capabilities are anticipated to be insufficient in their quest for Super Bowl success on Sunday night. The 49ers’ defensive strength has been a consistent theme this season, as they’ve held opponents to 21 points or fewer in 13 of their 18 games. This formidable defense is expected to exert intense pressure on Lions’ quarterback Jared Goff, who is known to struggle in outdoor conditions.

Goff is likely to encounter a multitude of challenges, potentially leading him to rely on check-downs, throwaways, or even precarious decisions amidst the 49ers’ aggressive defense. Expecting a cautious approach from Goff under pressure, the Lions might shift their focus to a run-oriented offense to capitalize on any perceived weaknesses in the 49ers’ run defense. The Lions should be able to maintain a competitive stance in this aspect.

The prediction for the game is that the Detroit Lions will cover the spread, and the total score will be under 52.0 points.

  • Betting prediction: Detroit Lions +7.0
  • Odds: 2.00 (+100 American)
  • Betting prediction: Under 52.0 points
  • Odds: 1.92 (-109 American)
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